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Publikationen 1988 - 1992

1992

24. Synthesis and useful reactions of organosilicon polymeric precursors for ceramics:
D. Seyferth, C. Strohmann, H.J. Tracy, J.L. Robison, Report 1992, 92, Abstr. No. 241, 210.
23. Synthesis and useful reactions of organosilicon polymeric precursors for ceramics:
D. Seyferth, C. Strohmann, H.J. Tracy, J.L. Robison, Mater. Res. Soc. Symp. Proc. 1992, 249, 3-14.
22. Bis[3,4,5,6-tetrabromo-1,2-benzenediolato(2-)}(pyrrolidiniomethyl)silicate- acetonitrile-solvate, [(C6Br4O2)2SiCH2(H)NC4H8CH3CN]: Synthesis and crystal and molecular structure of a zwitterionic λ5-spirosilicate:
R. Tacke, J. Sperlich, C. Strohmann, B. Frank, G. Mattern, Z. Kristallogr. 1992, 199, 91-98. pdf
21. Stereoselective interaction of procyclidine, hexahydrodifenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors:
M. Waelbroeck, J. Camus, M. Tastenoy, E. Mutschler, C. Strohmann, R. Tacke, L. Schjelderup, A. Aasen, G. Lambrecht, J. Christophe, Eur. J. Pharmacol. 1992, 227, 33-42. pdf

 

1991

20. Preparation of quaternized 1,1-dicycloalkyl-4-amino-2-butyn-1-ols as selective antimuscarinics,
G. Lambrecht, E. Mutschler, R. Tacke, L.K. Choo, C. Strohmann, Ger. Offen. 1991.
19. Cyclohexyl(4-fluorophenyl)(3-piperidinopropyl)silanol [p-fluoro-hexahydrosila-dife-nidol (p-F-HHSiD)] and derivatives: synthesis and antimuscarinic properties:
R. Tacke, K. Mahner, C. Strohmann, B. Forth, E. Mutschler, T. Friebe, G. Lambrecht, J. Organomet. Chem. 1991, 417, 339-353.
18. Bis[2,3-naphthalenediolato(2-)](pyrrolidiniomethyl)silicat-Acetonitril-Solvat: Synthese sowie Kristall und Molekülstruktur eines zwitterionischen λ5-Spirosilicats:
R. Tacke, J. Sperlich, C. Strohmann, G. Mattern, Chem. Ber. 1991, 124, 1491-1496. pdf
17. Bioorganosilicon chemistry - recent results:
R. Tacke, S. Brakmann, M. Kropfgans, C. Strohmann, F. Wuttke, G. Lambrecht, E. Mutschler, P. Proksch, H.-M. Schiebel, L. Witte in Frontiers of Organosilicon Chemistry (A.R. Bassindale and P.P.Gaspar, Hrsg.), Bookcraft (Bath) Ltd., Cambridge (England) 1991, S.218-228.
16. Enantiomers of the Muscarinic Antagonist 1-Cyclohexyl-1-(4-fluorophenyl)-4-piperidino-1-butanol (p-Fluorohexahydrodifenidol): Synthesis, Absolute Configuration, and Enantiomeric Purity:
C. Strohmann, S. Bauerecker, H.-K. Cammenga, P.G. Jones, E. Mutschler, G. Lambrecht, R. Tacke, Liebigs Ann. Chem. 1991, 523-527. pdf
15. Stereoselectivity of (R)- and (S)-hexahydro-difenidol binding to neuroblastoma M1, cardiac M2, pancreatic M3, and striatum M4 muscarinic receptors:
M. Waelbroeck, J. Camus, M. Tastenoy, E. Mutschler, C. Strohmann, R. Tacke, G. Lambrecht, J. Chistophe, Chirality 1991, 3, 118-123. pdf
14. Binding affinities of hexahydro-difenidol and hexahydro-sila-difenidol analogs at four muscarinic receptor subtypes: constitutional and stereochemical aspects:
M. Waelbroeck, J. Camus, M. Tastenoy, E. Mutschler, C. Strohmann, R. Tacke, G. Lambrecht, J. Chistophe, Eur. J. Pharmacol. 1991, 206, 95-103.
13. Bis(2,3-naphthalindiolato)[2-(pyrrolidinio)ethyl]silicat: Synthese und strukturelle Charakterisierung eines zwitterionischen λ5-Spirosilicats:
C. Strohmann, G. Mattern, W.F. Kuhs, R. Tacke, J. Organomet. Chem. 1991, 403, 63-71.
12. Selective labeling of muscarinic M1 receptors in calf superior cervical ganglia by [3H](±)-telenzepine:
R. Feifel, J.F. Rodrigues de Miranda, C. Strohmann, R. Tacke, A.J. Aasen, E. Mutschler, G. Lambrecht, Eur. J. Pharmacol. 1991, 195, 115-123. pdf

 

1990

11. Pharmacokinetic properties of the antimuscarinic drug [3H]-hexahydro-sila-difenidol in the rat:
N.M. Rettenmayr, J.F. Rodrigues de Miranda, N.V.M. Rijntjes, F.G.M. Russel, C.A.M. van Ginneken, C. Strohmann, R. Tacke, G. Lambrecht, E. Mutschler, Naunyn-Schmiedeberg´s Arch. Pharmacol. 1990, 342, 146-152. pdf
10. Stereoselective inhibition of muscarinic receptor subtypes by the enantiomers of hexahydro-difenidol and acetylenic analogues:
R. Feifel, M. Wagner-Röder, C. Strohmann, R. Tacke, M. Waelbroeck, J. Christophe, E. Mutschler, G. Lambrecht, Br. J. Pharmacol. 1990, 99, 455.

 

1989

9. Stereoselectivity of the interaction of muscarinic antagonists with their receptors:
M. Waelbroeck, M. Tastenoy, J. Camus, R. Feifel, E. Mutschler, C. Strohmann, R. Tacke, G. Lambrecht, J. Christophe, Trends Pharmacol. Sci. 1989, 10, Suppl. 65-69.
8. Pharmacology of hexahydrodifenidol, hexahydrosiladifenidol and related selective muscarinic antagonists:
G. Lambrecht, R. Feifel, U. Moser, M. Wagner-Röder, L.K. Choo, J. Camus, M. Tastenoy, M. Waelbroeck, C. Strohmann, R. Tacke, J.F. Rodrigues de Miranda, J. Christophe, E. Mutschler, Trends Pharmacol. Sci. 1989, 10, Suppl. 60-64.
7. Affinity profiles of hexahydro-sila-difenidol analogs at muscarinic receptor subtypes:
G. Lambrecht, R. Feifel, M. Wagner-Röder, C. Strohmann, H. Zilch, R. Tacke, M. Waelbroeck, J. Christophe, H. Boddeke, E. Mutschler, Eur. J. Pharmacol. 1989, 168, 71-80. pdf
6. Binding and functional properties of antimuscarinics of the hexocyclium/sila- hexocyclium and hexahydro-diphenidol/hexahydro-sila-difenidol type to muscarinic receptor subtypes:
M. Waelbroeck, M. Tastenoy, J. Camus, J. Christophe, C. Strohmann, H. Linoh, H. Zilch, R.Tacke, E. Mutschler, G. Lambrecht, Br. J. Pharmacol. 1989, 98, 197-205.
5. Darstellung und Eigenschaften der Enantiomere des selektiven Antimuscarinikums 1-Cyclohexyl-1-phenyl-4-piperidino-1-butanol (Hexahydro-Difenidol):
R. Tacke, C. Strohmann, S. Sarge, H.K. Cammenga, D. Schomburg, E. Mutschler, G. Lambrecht, Liebigs Ann. Chem. 1989, 137-143. pdf
4. Synthesis of the selective antimuscarinic agent 4-{[cyclohexylhydroxy(2-methoxy-phenyl)silyl]methyl}-1,1-dimethylpiperazinium methyl sulfate (o-methoxysila- hexocyclium methyl sulfate):
R. Tacke, K. Rafeiner, C. Strohmann, E. Mutschler, G. Lambrecht, Appl. Organomet. Chem. 1989, 3, 129-132.

 

1988

3. Presynaptic muscarinic receptors mediating inhibition of neurogenic contractions in rabbit vas deferens are of the ganglionic M1-type:
M. Eltze, G. Gmelin, J. Wess, C. Strohmann, R. Tacke, E. Mutschler, G. Lambrecht, Eur. J. Pharmacol. 1988, 158, 233-242. pdf
2. p-Fluorohexahydro-siladifenidol: The first M2β-selective muscarinic antagonist:
G. Lambrecht, R. Feifel, B. Forth, C. Strohmann, R. Tacke, E. Mutschler, Eur. J. Pharmacol. 1988, 152, 193-194. pdf
1. σ-Methoxy-sila-hexocyclium: a new quaternary M1-selective muscarinic antagonist:   
G. Lambrecht, G. Gmelin, K. Rafeiner, C. Strohmann, R. Tacke, E. Mutschler, Eur. J. Pharmacol. 1988, 151, 155-156. pdf

 

 

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